A reticular cell is a type of fibroblast that synthesizes collagen alpha-1(III) and uses it to produce reticular fibers. The cell surrounds the fibers with its cytoplasm, isolating it from other tissue components and cells.[1] Reticular cells provide structural support, since they produce and maintain the thin networks of fibres that are a framework for most lymphoid organs.
They are found in many tissues including the spleen, lymph nodes and lymph nodules. They also direct B cells and T cells to specific regions within the tissue.
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